Hydrophobic Interaction Chromatography
Separate proteins based on hydrophobicity differences. Excellent for aggregate removal, variant separation, and polishing in mAb processes.
Hydrophobicity Scale
ButylLow-Medium
PhenylMedium
OctylHigh
HIC Products
Select based on your target protein hydrophobicity and separation requirements.
Sepax Phenyl HP
PopularMedium hydrophobicity resin ideal for mAb aggregate removal and polishing
mAb polishingAggregate removal
Ligand
Phenyl
Hydrophobicity
Medium
Sepax Butyl HP
PopularLower hydrophobicity for gentle separation of sensitive proteins
Sensitive proteinsMild conditions
Ligand
Butyl
Hydrophobicity
Low-Medium
Sepax Octyl HP
Higher hydrophobicity for strongly hydrophobic proteins
Hydrophobic proteinsMembrane proteins
Ligand
Octyl
Hydrophobicity
High