Separation is our science, collaboration is our strategy
Peptide Purification

Insulin / GLP-1 / Peptide Solutions

High-resolution purification for therapeutic peptides. Our CEX and RPC resins deliver the selectivity required for insulin, GLP-1 agonists, and synthetic peptide APIs with > 99% purity.

Peptide Purification Process
CEX capture + RPC polish workflow
1
1. Capture
Cation Exchange
~85%
Purity
2
2. Purification
Reversed Phase
>99%
Purity
3
3. Polish
SEC or IEX
API Grade
Purity

Peptide Purification Workflow

CEX Capture + RPC High-Resolution Strategy

CEX Resins
RPC Resins
SEC or IEX
Cation
Exchange
Capture
Buffer
Exchange
Reversed
Phase
Polish
Final
Polish
Formulation
Captures
peptide by charge
High resolution
separation of
variants

Peptide Types

Specialized workflows for different peptide therapeutics.

Insulin

Recombinant human insulin and analogs (glargine, lispro, aspart)

CEX CaptureRPC PolishSEC Final
GLP-1 Agonists

Semaglutide, liraglutide, tirzepatide purification

CEX CaptureRPC PolishIEX Final
Synthetic Peptides

Custom therapeutic peptides and peptide APIs

IEX CaptureRPC PolishDesalting