AAV Purification
AAV Purification Solutions
Serotype-specific affinity capture combined with high-resolution ion exchange for full/empty capsid separation. Our platform supports AAV2, AAV5, AAV8, AAV9 and other common serotypes.
AAV Purification Process
Affinity capture + IEX polish workflow
1
1. Capture
Affinity
~80%
Target
2
2. Polishing
AIEX
>90%
Target
3
3. Analysis
SEC/AUC
Full/Empty Ratio
Target
AAV Purification Workflow
Affinity Capture + IEX Full/Empty Separation
AAV Affinity Resins
AIEX Resins
SEC Resins
Affinity
Capture
Buffer
Exchange
Anion
Exchange
Polish
SEC
/
AUC
Analysis
Formulation
Serotype-specific
capture
Separates
full capsids
from empty
Supported Serotypes
Our AAV purification platform supports multiple serotypes.
AAV2
CNS, liver, muscle targeting
AAV5
CNS, retina applications
AAV8
Liver-directed gene therapy
AAV9
Systemic, CNS applications
Recommended Products
Key resins for AAV purification workflows.